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Large instrument and equipment sharing

The open service platform of large instrument and equipment in Institute of Laboratory Animal Sciences can provide the sharing of molecular imaging technology for the innovative research of human cardiovascular and cerebrovascular diseases, tumors, nervous system diseases, etc. At present, it has provided the analysis of disease models for national subjects including tumors, heart disease, hypertension, etc.; Animal models of human diseases develop medical analysis platform through the establishment of animal model, identification and repository construction, providing resources animal models for medical and pharmaceutical research disease, can undertake disease pathological phenotypes in the model identification, pathological mechanism research, laboratory animal pathology detection and drug safety evaluation and other technical services.

 

At present, the institute has large instruments as follows:

Instrument and Equipment Name

Platform

Service content (analysis and test items, etc.)

Contact

Telephone

Molecular image analyzer for small animal-PET/CT system

Instrument center - laboratory animal image analysis platform

CT/PET

Gao Kai

010-67787336

Automatic biochemical analyzer

Instrument center - platform for preclinical evaluation of drugs

An instrument for the detection and analysis of vital chemicals, which provides information for the clinical diagnosis, treatment, prognosis and health status of diseases.

Gao Jie

010-63038194

High-speed freezing centrifuge

Instrument center -  platform for creating genetically engineered animals

The separation of nucleic acid, protein and cell can be realized. The patented software can simulate different separation experiments, and save the time of groping conditions and precious samples.

Dong Wei

010-87778442

High resolution ultrasound imaging system for small animals

Instrument center - laboratory animal image analysis platform

Research Objects:

Mice ranging from embryos to adults, and small animal models ranging from small zebrafish to large rabbits.  

Vevo2100 ultrahigh resolution ultrasound imaging, anatomy, function, physiology, Molecular level data

Ultrasonic imaging;  

Analysis and measurement software.

Dong Wei

010-87778442

Small animal magnetic resonance imager

Instrument center - laboratory animal image analysis platform

Small animal magnetic resonance imager is mainly used for in vivo magnetic resonance imaging of mice and rats, and its main applications are as follows:

1. Study on animal model of head tumor;   

2. Study on animal models of cerebral thrombosis and cerebral infarction;   

3. Liver tumors, fatty liver, and other liver diseases;   

4. Subcutaneous tumor research;   

5. Research on targeted drugs (nanomaterials, MRI contrast agent);  

6. Tumor research

7. Cardiovascular disease research

8. Targeted research based on magnetic resonance contrast agent

9. Pathological studies, obesity studies

Gao Kai

010-67787336

Observation of living cells under an inverted microscope

Instrument center -  platform for creating genetically engineered animals

Inverted microscope can be used for observation of microorganism, cell, bacteria, tissue culture, suspension and sediment in medical and health institutions, universities and research institutes. The process of cell and bacteria reproduction and division in culture medium can be continuously observed, and any form in this process can be photographed.

It is widely used in cytology, parasitology, oncology, immunology, genetic engineering, industrial microbiology, botany and other fields.

Dong Wei

010-87778442

Large tissue stereoscopic tomography analyzer

Instrument center - laboratory animal image analysis platform

CT scan analysis of small animals

Gao Kai

010-67787336

Microtome for frozen tissue

Instrument center - platform for pathological analysis of laboratory animals

CM3600 large freezing microtome can undertake the slicing of adhesive tape.

Li Yanhong

010-87778141

Implantable telemetry system for physiological signals

Instrument center - platform for preclinical evaluation of drugs

Telemetry of physiological signals in laboratory animals

Gao Jie

010-63038194

EnSpire multifunctional microporous plate detector

Instrument center - laboratory animal quality assurance platform

ELISA high throughput detection

Xiang Zhiguang

010-67776438

Flow cytometry instrument

Instrument center - experimental platform for infectious diseases

Immunoassay

Chen Ting

010-67776838

Microoperating System (Leica microscope)

Instrument center - north laboratory animal resources platform

Development of transgenic mice

Lu Tianyu

010-67779073

Portable X-ray machine

Instrument center - laboratory animal surgery platform

Animal image observation

Zhao Linna

010-67770053

Forward fluorescence microscope

Instrument center -  platform for creating genetically engineered animals

Pathological analysis

Wang Chao

010-67762060

Lung function recorder in awake animals

Instrument center - north laboratory animal resources platform

It is used to establish models of asthma, hand-foot-and-mouth disease

Li Yanhong

010-67761551

Hydrogen peroxide steam generator

Instrument center - laboratory platform for infectious diseases

Biosafety laboratory disinfection

Qiao Hongwei

010-67770859

Flow cytometry instrument

Instrument center - laboratory animal immunoassay platform

Cell cycle detection, cell apoptosis detection, immune cell analysis, target cell sorting, etc.

Bai Lin

010-67770311

Heavy and transitional gliding microtome

Instrument center - platform for pathological analysis of laboratory animals

The pathological analysis and pathological diagnosis service of the laboratory pathological analysis platform

Li Yanhong

010-67761551

Aerosol exposure system

Instrument center - laboratory platform for infectious diseases

For the establishment of animal models of infectious diseases

Gao Hong

010-67770859

Energy monitoring and metabolic analysis system for rodent laboratory animals

Instrument center - behavior analysis of laboratory animal platform

For metabolic disease research

Wang Xinpei

010-67770023
Cognitive system of Non-human primates

Instrument center - behavior analysis of laboratory animal platform

For Parkinson's disease, motor behavior research

Dou Changsong

010-63013095

Flow cytometry instrument

Instrument center - anthropogenic animal model platform

For tumor PDX research

Li Mengyuan

010-67779532

Panoramic bright field imaging analysis system

Instrument center - platform for pathological analysis of laboratory animals

Pathological analysis, image collection and quantitative analysis of HE staining, immunohistochemical staining and immunocytochemical staining results are included

Zhang Ling

010-87778141

Automatic monitoring system for mycobacterium culture

Instrument center - experimental platform for infectious diseases

Rapid culture, identification and drug sensitivity tests of mycobacterium tuberculosis were carried out for sputum, chest and abdomen fluid, body fluid, spinal fluid, body fluid, cerebrospinal fluid, tissue mass specimens and other non-blood specimens

Tang Jun

010-67776279

Multispectral slice imaging system

Instrument center - behavior analysis of laboratory animal platform

Whole cell recording of neurons in vitro slice in different brain regions of central nervous system of rodent and the electrophysiological recording of neurons, synapses and local nerve microcircuits:

the resting membrane potential of neurons, single action potential and its differential curve, rate of change, excitatory postsynaptic potential, inhibitory postsynaptic potential, etc.

Zhang Yu

010-63013095

Digital PCR instrument

Instrument center - anthropogenic animal model platform

Detection of gene copy number, rare mutation detection, gene expression analysis

Li Mengyuan

010-67779532

PM2.5 real-time online concentration and contamination system

Instrument center - north laboratory animal resources platform

Used for particle exposure, dust exposure and liquid aerosol exposure

Guo Jianguo

010-87778141

High content cell imaging analysis system

Instrument center - anthropogenic animal model platform

Used for real-time observation and video recording of living cells, fluorescence and bright field photography

Li Haifeng

010-67779073

Neural information acquisition and analysis system

Instrument center -  platform for creating genetically engineered animals

The firing signals of neurons were collected and analyzed

Dong Wei 010-87778442

Image analyzer of enzyme-linked Immunodotting

Instrument center - laboratory animal immunoassay platform

Analyze and test virus spot, colony, clone spot and other microorganism experiment

Shi Na

010-67719670

Suspension biochip system

Instrument center - laboratory animal immunoassay platform

Multichannel high-throughput and high-sensitivity analysis of nucleic acids, enzymes, receptors, antibodies and antigens

Shi Na

 
010-67719670

In-vivo animal imaging system

Instrument center - laboratory animal image analysis platform

1. For all kinds of chemiluminescence imaging,

2. For multicolor fluorescence imaging,

3. DNA/RNA and protein gel electrophoresis imaging for various dyes;  

4. Used for Western, Norther, Southern, Dot/Slotblot and other hybrid membrane imaging;  

5. Other applications, such as colony counting in petri dishes, labeling plate, autoradiography film analysis, etc.

Shi Xudong

010-67787336

Slice scanner

Instrument center - platform for pathological analysis of laboratory animals

Scanning slice with bright field fluorescence.

Qu Yajin

13641271425