品系编号：ILAS-002-W-000153

品系名称：WKY/N大鼠

英文名称：WKY/N rat

其它名称：

物种描述：近交系

传代：

外观特征：毛色：。

遗传特征：染色体为21对?

品系来源：National Institutes of Health in 1971 from 封闭群 Wistar stock from Kyoto School of Medicine. 近交系 as a normotensive control strain for SHR (Hanesn et al 1973), though there is some controversy about the validity of such use (see Rapp 1987). Johnson et al (1992) found large genetic differences using restriction fragment length polymorphisms between WKY and SHR, comparable to the maximum divergence possible between unrelated humans. Also, breeding stock of ths strain was distributed before F20, possibly resulting in the emergence of a number of strains or substrains (Kurtz and Morris 1987, Kurtz et al 1989). It is therefore essential that subline codes are always used in designating this strain.

相关亚系：

生物学特征：大鼠繁殖快。肠道较短，盲肠较大，但盲肠功能不发达。性情较凶猛、抗病力强。无胆囊。不能呕吐。不耐饥饿，肠内能合成维生素C。双子宫。胸部和鼠蹊部各有三对乳头。胰腺十分分散，位于胃和十二指肠弯曲处。

寿命与疾病：寿命3～4年。

研究应用：生物医学研究。

饲养与繁殖：大鼠2月龄时性成熟，性周期4天左右，妊娠期20（19～22），哺乳期21天，每天产仔平均8只，为全年、多发情性动物。?

保种单位：http://dvrnet.ors.od.nih.gov/ratcenter/index.html>NIH Autoimmune Rat Model Repository and Development Center, http://www.nrrrc.missouri.edu/StrainInfo.asp?appn=190>Rat Resource and Research Center

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