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2010

品系编号:ILAS-002-S-000600

品系名称:SS大鼠

英文名称:SS rat

其它名称:

物种描述:近交系

传代:

外观特征:毛色:。

遗传特征:染色体为21对?

品系来源:Rapp from a colony of Sprague-Dawley 封闭群 rats developed by LK Dahl, Brookhaven National Laboratories, Upton, New York, selected for sensitivity to salt-induced hypertension (Dahl et al 1962a,b, Rapp 1982). Also designated S/JR by Rapp (1984), who gives an extensive review of the characteristics of the strain, and Dahl S by Mollegard, Copenhagen. Note that the Dahl selected strain has been independently 近交系 at the NIH, and designated DSS/N. There is likely to be confusion among these colonies unless considerable care is taken with nomenclature. Stlezin et al (1992) found that SS and SR had about 80% of DNA fingerprint bands in common, compared with 50% between SHR and WKY. According to Ginn et al, (1993) analysis of RFLPs and microsatellites suggest that SR is a reasonably good control strain for SS, though crosses between SS and unrelated normotensive strains will be useful in dientifying the loci responsible for salt-induced hypertension.

相关亚系:

生物学特征:大鼠繁殖快。肠道较短,盲肠较大,但盲肠功能不发达。性情较凶猛、抗病力强。无胆囊。不能呕吐。不耐饥饿,肠内能合成维生素C。双子宫。胸部和鼠蹊部各有三对乳头。胰腺十分分散,位于胃和十二指肠弯曲处。

寿命与疾病:寿命3~4年。

研究应用:生物医学研究。

饲养与繁殖:大鼠2月龄时性成熟,性周期4天左右,妊娠期20(19~22),哺乳期21天,每天产仔平均8只,为全年、多发情性动物。?

保种单位:Brookhaven National Laboratories, Upton, New York

参考资料:

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