品系编号：ILAS-002-L-000117

品系名称：LEW-Tg(HLA-B*2705m1,B2M)133-1Trg大鼠

英文名称：LEW-Tg(HLA-B*2705m1,B2M)133-1Trg rat

其它名称：

物种描述：转基因

传代：

外观特征：毛色：。

遗传特征：染色体为21对?

品系来源：This strain was made by pronuclear injection into Lewis embryos. The embryos were co-injected with DNA fragments containing the HLA-B*2705 human gene and the human beta-2-microglobulin gene. Founder 133-1 was selected and carrier animals from this founder were mated and bred to homozygosity. The strain was transferred from Dr. Joel Taurog, University of Texas Southwestern Medical School in Dallas to the Rat Resource and Research Center in 2002. The strain has been maintained by sibling mating.

相关亚系：

生物学特征：大鼠繁殖快。肠道较短，盲肠较大，但盲肠功能不发达。性情较凶猛、抗病力强。无胆囊。不能呕吐。不耐饥饿，肠内能合成维生素C。双子宫。胸部和鼠蹊部各有三对乳头。胰腺十分分散，位于胃和十二指肠弯曲处。

寿命与疾病：寿命3～4年。

研究应用：生物医学研究。

饲养与繁殖：大鼠2月龄时性成熟，性周期4天左右，妊娠期20（19～22），哺乳期21天，每天产仔平均8只，为全年、多发情性动物。?

保种单位：http://www.nrrrc.missouri.edu/StrainInfo.asp?appn=43>Rat Resource and Research Center

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