品系编号：ILAS-002-L-000116

品系名称：LEW-Tg(HLA-B*0702,B2M)120-4Trg大鼠

英文名称：LEW-Tg(HLA-B*0702,B2M)120-4Trg rat

其它名称：

物种描述：转基因

传代：

外观特征：毛色：。

遗传特征：染色体为21对?

品系来源：Lewis from CRL were used as the background strain. This strain was made by pronuclear injection into Lewis embryos. The embryos were coinjected with DNA fragments containing the HLA-B*0702 human gene and the human beta-2-microglobulin gene. Founder 120-4 was selected and carrier animals from this founder were mated and this strain was bred to homozygosity.

相关亚系：

生物学特征：大鼠繁殖快。肠道较短，盲肠较大，但盲肠功能不发达。性情较凶猛、抗病力强。无胆囊。不能呕吐。不耐饥饿，肠内能合成维生素C。双子宫。胸部和鼠蹊部各有三对乳头。胰腺十分分散，位于胃和十二指肠弯曲处。

寿命与疾病：寿命3～4年。

研究应用：生物医学研究。

饲养与繁殖：大鼠2月龄时性成熟，性周期4天左右，妊娠期20（19～22），哺乳期21天，每天产仔平均8只，为全年、多发情性动物。?

保种单位：http://www.nrrrc.missouri.edu/StrainInfo.asp?appn=42>Rat Resource and Research Center

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