This research group mainly researches the pathogenesis of cardiovascular diseases and related animal models, including the mechanism of salt metabolism regulating blood pressure and developing target organ injury through sodium absorption and excretion as well as chronic inflammation. The pathogenesis of cardiovascular diseases such as atherosclerosis, cardiomyopathy and large hemangioma caused by inflammatory reaction and metabolic disorder of the body; They carry out the production of animal models of genetic engineering, chemical/physical/food induction, surgical operation, hypertension, cardiomyopathy, hemangioma and other mice and determine their basic physiological functions. There are more than 30 animal models of dopamine receptor, gastrin receptor, inflammatory factor, sodium/potassium ion channel, metabolic regulator and other related genetic engineering, and more than 10 non-genetic engineering model preparation techniques.